In a prospective cohort study of 14,207 middle-aged participants, those who drank any amount of coffee each day had a 15% lower risk of acute kidney damage, with the largest reduction seen in the group drinking two up to three glasses a day.
Higher coffee intake is associated with a lower risk of accidental acute kidney damage and may be an option for cardiorenal protection through diet. Image Credit: Sci-News.com.
Coffee is one of the most widely consumed beverages in the world.
It contains a wide variety of compounds, including caffeine, diterpenes and chlorogenic acid, which are fully developed after the roasting process and have been reported to have a range of health benefits.
Regular coffee consumption is associated with the prevention of chronic and degenerative diseases, including type 2 diabetes, cardiovascular disease and liver disease.
A previous population-based study found that higher daily self-reported coffee consumption was associated with a lower risk of incidental chronic kidney disease after adjustments for demographic, clinical and dietary factors were made.
Thus, regular coffee consumption has a strong potential to reduce the risk of progressive kidney disease.
“We can now add a possible reduction in the risk of acute kidney damage to the growing list of health benefits of caffeine,” said Professor Chirag Parih, director of nephrology at Johns Hopkins University School of Medicine.
“Acute kidney damage, as described by the National Kidney Foundation, is a sudden episode of kidney failure or kidney damage that occurs within hours or days.”
“This causes waste products to accumulate in the blood, which makes it difficult for the kidneys to maintain the right balance of fluids in the body.
“Symptoms of acute kidney damage vary depending on the cause and may include: too little urine leaving the body; swelling of the legs and ankles and around the eyes; fatigue; Lack of air; confusion; nausea; chest pain; and in severe cases, seizures or coma. “
“The disorder is most commonly seen in hospitalized patients whose kidneys are affected by medical and surgical stress and complications.”
In their study, Professor Parich and colleagues analyzed data from the Community Atherosclerosis Risk Study (ARIC), an ongoing study of cardiovascular disease in four communities in the United States.
They assessed 14,207 adult participants employed between 1987 and 1989 with an average age of 54 and the following self-approved coffee drinking habits: 27% had never drunk coffee; 14% drink 3 glasses a day.
During the study period, 1694 cases of acute renal damage were registered.
When demographics, socioeconomic status, lifestyle and nutritional factors are taken into account, there is a 15% lower risk of acute kidney damage for participants who consume any amount of coffee than those who do not. .
When adjusted for additional comorbidities such as blood pressure, body mass index (BMI), diabetes status, antihypertensive use and kidney function, coffee drinkers still have an 11% lower risk of developing acute kidney damage compared to those who do. no.
“We suspect that the reason coffee affects the risk of acute kidney damage may be that either the biologically active compounds combined with caffeine or simply caffeine itself improves the perfusion and use of oxygen in the kidneys,” said Professor Parich.
“Good kidney function and tolerance to acute kidney damage depend on a stable blood supply and oxygen.”
“More research is needed to determine the possible defense mechanisms of coffee consumption for the kidneys, especially at the cellular level,” he added.
“It is postulated that caffeine inhibits the production of molecules that cause chemical imbalances and the use of too much oxygen in the kidneys. Maybe caffeine helps the kidneys maintain a more stable system.
The results are published in the journal Kidney International Reports.
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Kalie L. Tommerdahl et al. Coffee consumption can alleviate the risk of acute kidney damage: Results of a study of the risk of atherosclerosis in communities. Kidney International Reports, published online on May 5, 2022; doi: 10.1016 / j.ekir.2022.04.091
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